منابع مشابه
It Takes KASH to Hitch to the SUN
Observations stretching back more than two decades have suggested that nuclei and nuclear components are mechanically coupled to the cytoskeleton. In multicellular organisms, this mechanical coupling may extend beyond the plasma membrane to the extracellular matrix and adjacent cells. More recently, studies on a variety of human diseases associated with defects in nuclear envelope (NE) proteins...
متن کاملKASH and SUN proteins
KASH and SUN proteins Quick guides at-bat, including which fielders were involved, and so on. At that point, I was amused to see that my friend Kyle was also keeping score, but that he marked every at-bat with a simple and uninformative ‘X’ when each batter was retired; consequently, his whole data sheet on the opposing team was just one string of Xs after another. Although I was feeling the su...
متن کاملIt takes two to tango
The vertebrate inner ear has time and again surprised neurobiologists by adding new wrinkles to known mechanisms of cellular signaling. among those surprises, was the discovery that nicotinic acetylcholine receptors (related to those that excite muscle) inhibit cochlear hair cells when acetylcholine (aCh) is released from efferent neurons. Inhibition occurs because calcium entering through the ...
متن کاملIt Takes T to Tango
Of three recently cloned T-type voltage-gated calcium channels, alpha(1g) is most likely responsible for burst firing in thalamic relay cells. These neurons burst during various thalamocortical oscillations including absence seizures. In this issue of Neuron, Kim et al. inactivated alpha(1g), and resultant mice were deficient in relay cell bursting and resistant to GABA(B) receptor-dependent ab...
متن کاملIt takes the time that it takes.
It was five days before my first Christmas in Perth, Australia, and our family had begun to arrive the night before. As the rest of household slept, I quickly threw on a skirt and tank top and left to attend the memorial service for one of my study participants, a 57-year old Anglican minister who had died from motor neurone disease (MND). Though I feared I would be late, I could see people mil...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Cell
سال: 2012
ISSN: 0092-8674
DOI: 10.1016/j.cell.2012.05.004